Episode 2: Effective in vivo binding energy landscape illustrates kinetic stability of RBPJ-DNA binding
https://organoids-ulm.com/wp-content/uploads/2025/05/News_Nat_Commun_2025_Huynh_RBPJ_binding_kinetics.mp4
Episode 3: Novel peptide targeting CXCR4 disrupt tumor-stroma crosstalk to eliminate migrating cancer stem cells
https://organoids-ulm.com/wp-content/uploads/2025/05/News_Harms.mp4
Alexander Kleger
Univ.-Prof. Dr.rer.med.
Position: Director of the Institute of Molecular Oncology and Stem Cell Biology, Division Chief Interdisciplinary Pancreatology, Head Core Facility Organoids
Research Focus: Pancreatic cancer, organoids, tumor microenvironment, pluripotent stem cells, clinical trials, therapy response prediction, DNA damage response
Research Focus: Pancreatic cancer, organoids, tumor microenvironment, pluripotent stem cells, clinical trials, therapy response prediction, DNA damage response
Markus Breunig
Jun.-Prof. Dr.rer.nat.
Position: Group leader at the Institute of Molecular Oncology and Stem Cell Biology
Research Focus: Pancreatic cancer, organoids, pluripotent stem cells, chip technology, bioprinting, highplex fluorescence staining, computational analysis
Research Focus: Pancreatic cancer, organoids, pluripotent stem cells, chip technology, bioprinting, highplex fluorescence staining, computational analysis
Mirja Harms
Dr.rer.nat.
Position: Group leader at the Institute of Molecular Virology
Research Focus: Colorectal cancer, organoids, co-cultures, peptide drug testing, CXCR4/GPCR signaling & targeting, molecular virology
Research Focus: Colorectal cancer, organoids, co-cultures, peptide drug testing, CXCR4/GPCR signaling & targeting, molecular virology
Ninel Azoitei
PD Dr.rer.nat.
Position: Scientific Coordinator at the Institute of Molecular Oncology and Stem Cell Biology
Focus: Project Management, Scientific Coordination
Focus: Project Management, Scientific Coordination
Nadine Gaisa
Univ.-Prof. Dr.med.
Position: Director of the Institute of Pathology
Research Focus: Urothelial cancer, clinical trials, biobanking, pathological samples, histopathology
Research Focus: Urothelial cancer, clinical trials, biobanking, pathological samples, histopathology
Michael Melzer
Dr.med.
Position: Group leader at the Clinic for Urology and Pediatric Urology
Research Focus: Urothelial cancer, organoids, assembloids, co-cultures, tumor microenvironment, pluripotent stem cells, therapy response prediction, scaffold development, computational analysis
Research Focus: Urothelial cancer, organoids, assembloids, co-cultures, tumor microenvironment, pluripotent stem cells, therapy response prediction, scaffold development, computational analysis
Sandra Heller
Dr.rer.nat.
Position: Group leader at the Institute of Molecular Oncology and Stem Cell Biology
Research Focus: Diabetes and endocrinology, organoids, pluripotent stem cells, chip technology, computational analysis
Research Focus: Diabetes and endocrinology, organoids, pluripotent stem cells, chip technology, computational analysis
Meike Hohwieler
Dr.rer.nat.
Position: Deputy head at the Institute of Molecular Oncology and Stem Cell Biology
Research Focus: Pancreatic cancer, organoids, assembloids, co-cultures, tumor microenvironment, pluripotent stem cells, chip technology
Research Focus: Pancreatic cancer, organoids, assembloids, co-cultures, tumor microenvironment, pluripotent stem cells, chip technology
Lukas Perkhofer
PD Dr.med. Dr. univ.
Position: Group leader at the Clinic for Internal Medicine I
Research Focus: Pancreatic and cholangiocellular carcinoma, clinical trials, therapy response prediction, DNA damage response, mouse models for pancreatic cancer
Research Focus: Pancreatic and cholangiocellular carcinoma, clinical trials, therapy response prediction, DNA damage response, mouse models for pancreatic cancer
Elodie Roger
Dr.rer.nat.
Position: Group leader at the Institute of Molecular Oncology and Stem Cell Biology
Research Focus: Pancreatic cancer, organoids, assembloids, co-cultures, tumor microenvironment, DNA damage response, highplex fluorescence staining, computational analysis, mouse models for pancreatic cancer
Research Focus: Pancreatic cancer, organoids, assembloids, co-cultures, tumor microenvironment, DNA damage response, highplex fluorescence staining, computational analysis, mouse models for pancreatic cancer
Tim Eiseler
Dr.rer.nat.
Position: Group leader at the Clinic for Internal Medicine I
Research Focus: Pancreatic cancer, cytoskeleton, kinases, extracellular vesicles, computational analysis, artificial intelligence
Research Focus: Pancreatic cancer, cytoskeleton, kinases, extracellular vesicles, computational analysis, artificial intelligence
Yuan-Na Lin
PD Dr.med. Dr. univ.
Position: Group leader at the Clinic for Internal Medicine I
Research Focus: Pancreatic cancer, organoids, assembloids, co-cultures, tumor microenvironment, immune checkpoints, chip technology
Research Focus: Pancreatic cancer, organoids, assembloids, co-cultures, tumor microenvironment, immune checkpoints, chip technology
Jan Münch
Univ.-Prof. Dr.rer.nat.
Position: Director of the Institute of Molecular Virology
Research Focus: Retroviruses & cancer, technology transfer and peptide drug development, CXCR4/ACKR3 signaling, receptor ligand interaction, molecular virology, nanotechnology
Research Focus: Retroviruses & cancer, technology transfer and peptide drug development, CXCR4/ACKR3 signaling, receptor ligand interaction, molecular virology, nanotechnology
Ion Cirstea
Dr.rer.nat.
Position: Group leader at the Institute of Molecular Endocrinology and Physiology
Research Focus: RASopathy-associated cancers, pluripotent stem cells, organoids, RAS signaling and drug development, mouse models for RASopathies
Research Focus: RASopathy-associated cancers, pluripotent stem cells, organoids, RAS signaling and drug development, mouse models for RASopathies
Jan Tuckermann
Univ.-Prof. Dr.rer.nat.
Position: Director of the Institute of Molecular Endocrinology and Physiology
Research Focus: Immune and cancer metabolism, inflammation, glucocorticoids and drug development, mouse models for bone integrity and insulin resistance
Research Focus: Immune and cancer metabolism, inflammation, glucocorticoids and drug development, mouse models for bone integrity and insulin resistance
Ani Grigoryan
Jun.-Prof. Dr.rer.nat.
Position: Group leader at the Institute of Molecular Medicine
Research Focus: Breast cancer and cancer dormancy, scaffold development, mouse models for bone metastasis, in vivo imaging
Research Focus: Breast cancer and cancer dormancy, scaffold development, mouse models for bone metastasis, in vivo imaging
Hartmut Geiger
Univ.-Prof. Dr.rer.nat.
Position: Director of the Institute of Molecular Medicine
Research Focus: Intestinal and hematopoietic malignancies during aging, organoids, intestinal and hematopoietic stem cells, technology transfer, lineage tracing
Research Focus: Intestinal and hematopoietic malignancies during aging, organoids, intestinal and hematopoietic stem cells, technology transfer, lineage tracing
Christof Gebhardt
Univ.-Prof. Dr.rer.nat.
Position: Director of the Institute of Experimental Physics
Research Focus: Transcription factor dynamics, single-molecule, super-resolution and light-sheet microscopy
Research Focus: Transcription factor dynamics, single-molecule, super-resolution and light-sheet microscopy
Franz Oswald
Apl.-Prof. Dr.rer.nat.
Position: Group leader at the Clinic for Internal Medicine I
Research Focus: Pancreatic cancer and hematopoietic malignancies, organoids, NOTCH-signaling and small molecules
Research Focus: Pancreatic cancer and hematopoietic malignancies, organoids, NOTCH-signaling and small molecules
Jessica Lindenmayer
Dr.rer.nat.
Position: Group leader, Deputy Head Core Facility Organoids
Research Focus: Organoids, pluripotent stem cells, therapy response prediction, semi-automated drug testing
Research Focus: Organoids, pluripotent stem cells, therapy response prediction, semi-automated drug testing
Medhanie Mulaw
Dr.rer.nat.
Position: Group leader, Head of Core Unit for Single Cell Sequencing
Research Focus: Colorectal cancer & hematopoietic malignancies, stem cells, advanced computational analysis, tool development, machine learning & AI
Research Focus: Colorectal cancer & hematopoietic malignancies, stem cells, advanced computational analysis, tool development, machine learning & AI